Searchable abstracts of presentations at key conferences in obesity

ob0002p5 | (1) | OU2020

Prevalence and determinants of metabolic health and different body composition phenotypes in a Maltese cohort

Agius Rachel , Pace Nikolai , Fava Stephen

The study determines the prevalence and lifestyle predictors of metabolic health (MH) among normal weight and obese individuals within a Maltese cohort using two main approaches a) the Metabolic Syndrome (Met-S) framework as per NCEP-ATPIII and b) Insulin Resistance (IR) as defined by HOMA-IR; and to determine which cut-off valueof HOMA-IR best predicts metabolic health. This was a cross sectional study. Subjects with a BMI <25 kg/m2 were considered normal weigh...

ob0003p3 | All items | OU2021

Gender differences in cardiometabolic abnormalities across different BMI categories

Agius Rachel , Pace Nikolai , Fava Stephen

Background: Not all obese individuals exhibit abnormal cardiometabolic parameters. These are termed as being metabolically healthy obese (MHO). Conversely some normal weight individuals exhibit adverse cardiometabolic parameters and are described as being metabolically unhealthy normal weight (MUHNW). Visceral adiposity is known to be strongly associated with cardiometabolic risk than subcutaneous adiposity. Furthermore, there are gender differences in distribution of fat and ...

ob0003p4 | All items | OU2021

Vitamin D Receptor (VDR) polymorphisms & metabolic health status in a maltese cohort

Micallef Kay Lee , Agius Rachel , Fava Stephen , Paul Pace Nikolai

Background: Several studies have investigated the association between vitamin D receptor (VDR) variants and the risk of cardiometabolic complications. The pleiotropic action of VDR in extra-skeletal tissues gives physiologic plausibility to the associations between VDR variants and metabolic health, particularly in obese individuals. Whilst multiple conflicting findings have been reported, clinical data has shown that despite an increase in physical activity and nurturing heal...

ob0002cd2.1 | Case Discussions: Complex Clinical Cases 2 | OU2020

Obstructive sleep apnoea is highly prevalent in a bariatric surgical population

Agius Rachel , Coelho Claudia , Crane James , Gupta Piya Sen , McGowan Barbara

Background: Obesity is an important predictor for development of obstructive sleep apnoea (OSA). Patients undergoing bariatric surgery are at increased risk of peri-operative morbidity from undiagnosed OSA. We aim to assess the prevalence and severity of OSA, and its association with the Epworth Screening Scale (ESS) in a bariatric surgical population.Methods: Retrospective study of adult patients who attended the Tier 4 Medical Obesity Clinic (MOC) at G...